ENFERMEDAD POLIGLANDULAR AUTOINMUNE PDF

Request PDF on ResearchGate | Síndrome poliglandular autoinmune tipo 1 y mutación CfsX | Polyglandular autoimmune Enfermedad de Addison. Síndrome poliglandular autoinmunitario tipo II (síndrome de Schmidt): enfermedad de Addison y tiroiditis de Síndrome pluriglandular autoinmune: Revisión. es El proyecto Euraps («Síndrome poliglandular autoinmune de tipo 1: una enfermedad infantil rara como modelo para la autoinmunidad») reunió a los mejores.

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Servicio de Medicina Interna II. Hospital Universitario San Carlos. The ethiology has drastically variated in the last century; being the origin almost exclusively tuberculous at the begining of and mainly autoimmune actually. Nowadays it is difficult to understand Addison’s disease out of the context of autoimmune polyglandular syndromes poliglandukar view of the frequent association to other endocrinopathys.

The present article pretends to realize a vision of the global disease related to these multiple endocrine deficits. La presencia de anticuerpos suele preceder al desarrollo enfermsdad la enfermedad, pero no todos los pacientes que los tienen van a padecerla.

No obstante, la poliglandluar suprarrenal ocupa el segundo lugar en frecuencia de enfermedad de Addison tras la adrenalitis autoinmune. Meningococemias, blastomicosis, histoplasmosis o turalosis 1,9. Frecuentemente por la toma de anticoagulantes 9, Destacamos la sarcoidosis, amiloidosis y hemocromatosis 3,9.

Insuficiencia suprarrenal primaria por adrenalitis autoimnume

Igualmente la rifampicina 16 o el acetato de ciproterona, son potencialmente productores de Addison. La primera se caracteriza por demencia, ceguera, tetraparesia e insuficiencia suprarrenal. El hipocortisolismo origina hipoglucemia.

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Los otros test son el test de la metopirona y el de la insulina, actualmente en desuso por poligkandular efectos secundarios. Unos niveles altos de ACTH con cortisol normal pudieran expresar una resistencia corticoadrenal en las primeras fases de la enfermedad autoinmune. Por ejemplo en Colls y cols.

EnUibo y cols.

Posteriormente, Chen y cols. Una vez recuperado el paciente se debe volver a las dosis de mantenimiento. Enfermedades de la corteza suprarrenal. Autoinmuns de Medicina Interna. N Engl J Med ; Masa suprarrenal e insuficiencia suprarrenal.

An Med Interna Madrid ; 3 2: Utility of CT in diagnosis and follow-up. Eur J Radiol ; Auhoinmune clues to the cause of Addison’s disease.

Am J Med ; Endocrine complications of the adquired inmunodeficiency syndrom. Arch Intern Med ; Recents advances in diagnosis and therapy of Addison’s disease. Advances in Thomas Addison’s Diseases. Thomas Addison’s Society ; 1: Primary adrenal insufficiency in patient with the adquired inmunodeficiency syndrome: J Clin Endocrinol Metab ; Metastases to the adrenal glands and the development of Addison’s Disease.

Cancer ; 54; Reversible adrenal insufficiency induced by Ketoconazole.

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Clin Endocrinol ; Hypoadrenalism Addison’s disease and antiphopholipid antibodies. J Rheumatol ; An Med Interna Madrid ; 12; Clin Endocrinol Metab ; Keljo D, Squires RH.

N Engl J Med ; 1: Glucocorticoids and blood pressure: Clin Sci ; The heart in endocrine and nutricional disorders. Knowlton AL, Baer L. Cardiac Faliure in Addison’s disease. Konstantin I, Papadopoulos, Hallegren B. Polyglandular autoinmune syndrome type II in patients with idiopathic Addison’s disease. Medicine ; 6 Arch Dis Child ; 68 6: Williams G, Dluhy R.

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Principios de Medicina Interna. Dose-response aspects in the clinical assessment of hypothalamo-pituitary-adrenal axis, and the low-dose ACTH test.

Eur J Endocrinol ; Exp Clin Endocrinol ; High diagnostic accuracy for idiopathic Addison’s disease with a sensitive radiobinding assay for antibodies against recombinant human hydroxilase. Autoantibodies to steroidogenic enzymes in autoinmune polyglandular syndrome, Addison’s disease and premature ovarian failure. J Clin Endocrinol Metab ; 81 5: The Lancet ; 21 5: Inmunoprecipitation assay for autoantibodies to steroid hydroxilase in autoinmune adrenal diseases.

Clin Chem ; 41 3: Autoantibodies to cytochrome P enzymes Pscc, P c17, P c21 in autoinmune polyglandular diseases types I y II and in isolated Addison’s disease. J Clin Endocrinol Metab ; 78 2: Adrenal cortex and steroid hydroxylase autoantibodies in adult patients with organ-specific autoimmune diseases: J Clin Endocrinol Metab ; 82 3: Senti S, Muller J. Morbus Addison in rahmen von polyglandularen autoinmunsyndromen: Penrice J, Nussey SS.

Recovery of adrenocortical function following treatment of tuberculous Addison’s disease. Effect of glucocorticoid replacement therapy on bone mineral density in patients with Addison’s disease.

Ann Intern Med ;